Enthalpically driven peptide stabilization by protective osmolytesw
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چکیده
COMMUNICATION Daniel Harries et al. Enthalpically driven peptide stabilization by protective osmolytes FEATURE ARTICLE Liu-Zhu Gong et al. The role of double hydrogen bonds in asymmetric direct aldol reactions catalyzed by amino amide derivatives
منابع مشابه
Enthalpically driven peptide stabilization by protective osmolytes.
We determined the added enthalpic and entropic contributions of protective osmolytes to the folding of a model peptide into its native beta-hairpin state. In contrast to entropically driven steric "crowding", this study shows that sugars and polyols can act as protective osmolytes by primarily diminishing the unfavourable enthalpic contribution to folding.
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